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Selenium derivatization of nucleic acids for crystallography
The high-resolution structure of the DNA (5′-GTGTACA-C-3′) with the selenium derivatization at the 2′-position of T2 was determined via MAD and SAD phasing. The selenium-derivatized structure (1.28 Å resolution) with the 2′-Se modification in the minor groove is isomorphorous to the native structure...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1802610/ https://ncbi.nlm.nih.gov/pubmed/17169989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1070 |
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