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Selenium derivatization of nucleic acids for crystallography

The high-resolution structure of the DNA (5′-GTGTACA-C-3′) with the selenium derivatization at the 2′-position of T2 was determined via MAD and SAD phasing. The selenium-derivatized structure (1.28 Å resolution) with the 2′-Se modification in the minor groove is isomorphorous to the native structure...

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Hlavní autoři: Jiang, Jiansheng, Sheng, Jia, Carrasco, Nicolas, Huang, Zhen
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1802610/
https://ncbi.nlm.nih.gov/pubmed/17169989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1070
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