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Efficient Substrate Cleavage Catalyzed by Hammerhead Ribozymes Derivatized with Selenium for X-ray Crystallography
As oxygen and selenium are in the same group (Family VI) in the Periodic Table, the site-specific mutagenesis at the atomic level by replacing RNA oxygen with selenium can provide insights on structure and function of catalytic RNAs. We report here the first Se-derivatized ribozymes transcribed with...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2519893/ https://ncbi.nlm.nih.gov/pubmed/16846240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060455m |
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