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Association of Dnmt3a and thymine DNA glycosylase links DNA methylation with base-excision repair

While methylcytosines serve as the fifth base encoding epigenetic information, they are also a dangerous endogenous mutagen due to their intrinsic instability. Methylcytosine undergoes spontaneous deamination, at a rate much higher than cytosine, to generate thymine. In mammals, two repair enzymes,...

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Detaylı Bibliyografya
Asıl Yazarlar: Li, Ya-Qiang, Zhou, Ping-Zhu, Zheng, Xiu-Dan, Walsh, Colum P., Xu, Guo-Liang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1802599/
https://ncbi.nlm.nih.gov/pubmed/17175537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1052
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