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The p16(INK4a) tumor suppressor controls p21(WAF1) induction in response to ultraviolet light
p16(INK4a) and p21(WAF1), two major cyclin-dependent kinase inhibitors, are the products of two tumor suppressor genes that play important roles in various cellular metabolic pathways. p21(WAF1) is up-regulated in response to different DNA damaging agents. While the activation of p21(WAF1) is p53-de...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1802571/ https://ncbi.nlm.nih.gov/pubmed/17158160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1075 |
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