Structural basis for activation of the therapeutic l-nucleoside analogs 3TC and troxacitabine by human deoxycytidine kinase

Gelijkaardige items

• Elucidation of Different Binding Modes of Purine Nucleosides to Human Deoxycytidine Kinase
  door: Sabini, Elisabetta, et al.
  Gepubliceerd in: (2008)
• The non-enantioselectivity property of human deoxycytidine kinase explained by structures of the enzyme in complex with l- and d-nucleosides
  door: Sabini, Elisabetta, et al.
  Gepubliceerd in: (2007)
• Extending thymidine kinase activity to the catalytic repertoire of human deoxycytidine kinase
  door: Hazra, Saugata, et al.
  Gepubliceerd in: (2009)
• The sugar ring of the nucleoside is required for productive substrate positioning in the active site of human deoxycytidine kinase (dCK): implications for the development of dCK-activated acyclic guanine analogs
  door: Hazra, Saugata, et al.
  Gepubliceerd in: (2010)
• Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogs
  door: Hazra, Saugata, et al.
  Gepubliceerd in: (2010)