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Cathepsin S is not crucial to TSHR processing and presentation in a murine model of Graves' disease
By regulating invariant (Ii) chain processing and MHC class II peptide loading, the endosomal protease cathepsin S (Cat S) has a potential role in autoimmune susceptibility. Indeed, Cat S null mice are resistant to I-Ab-restricted experimental myasthenia gravis due to inadequate peptide presentation...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Science Inc
2005
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1802445/ https://ncbi.nlm.nih.gov/pubmed/16313367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2005.02255.x |
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