Seven New Mutations in hMSH2, an HNPCC Gene, Identified by Denaturing Gradient-Gel Electrophoresis

Hereditary nonpolyposis colorectal cancer (HNPCC) is a relatively common autosomal dominant cancer-susceptibility condition. The recent isolation of the DNA mismatch repair genes (hMSH2, hMLH1, hPMS1, and hPMS2) responsible for HNPCC has allowed the search for germ-line mutations in affected individ...

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Bibliografski detalji
Glavni autori: Wijnen, Juul, Vasen, Hans, Khan, P. Meera, Menko, Fred H., van der Klift, Heleen, van Leeuwen, Claus, van den Broek, Marianne, van Leeuwen-Cornelisse, Inge, Nagengast, Fokko, Meijers-Heijboer, Anne, Lindhout, Dick, Griffioen, Gerrit, Cats, Annemieke, Kleibeuker, Jan, Varesco, Liliana, Bertario, Lucio, Bisgaard, Marie Luise, Mohr, Jan, Fodde, Riccardo
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801472/
https://ncbi.nlm.nih.gov/pubmed/7726159
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