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Mad2 is required for optimal hematopoiesis: Mad2 associates with c-Kit in MO7e cells
Mitotic arrest deficiency 2 (Mad2) is a component of mitotic spindle checkpoint proteins and is essential for accurate chromosome segregation. We investigated a role for Mad2 in hematopoiesis using Mad2-haploinsufficient (Mad2(+/−)) mice. Mad2(+/−) bone marrow (BM) and spleen manifested decreased ab...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1801064/ https://ncbi.nlm.nih.gov/pubmed/17038523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-06-030841 |
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