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Haplotype-based association analysis of the MAPT locus in Late Onset Alzheimer's disease

BACKGROUND: Late onset Alzheimer's disease (LOAD) is a common sporadic form of the illness, affecting individuals above the age of 65 yrs. A prominent hypothesis for the aetiopathology of Alzheimer's disease is that in the presence of a β-amyloid load, individuals expressing a pathogenic f...

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Main Authors: Mukherjee, Odity, Kauwe, John SK, Mayo, Kevin, Morris, John C, Goate, Alison M
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800865/
https://ncbi.nlm.nih.gov/pubmed/17266761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-8-3
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