Association of MAPT haplotypes with Alzheimer’s disease risk and MAPT brain gene expression levels

INTRODUCTION: MAPT encodes for tau, the predominant component of neurofibrillary tangles that are neuropathological hallmarks of Alzheimer’s disease (AD). Genetic association of MAPT variants with late-onset AD (LOAD) risk has been inconsistent, although insufficient power and incomplete assessment...

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Main Authors: Allen, Mariet, Kachadoorian, Michaela, Quicksall, Zachary, Zou, Fanggeng, Chai, High Seng, Younkin, Curtis, Crook, Julia E, Pankratz, V Shane, Carrasquillo, Minerva M, Krishnan, Siddharth, Nguyen, Thuy, Ma, Li, Malphrus, Kimberly, Lincoln, Sarah, Bisceglio, Gina, Kolbert, Christopher P, Jen, Jin, Mukherjee, Shubhabrata, Kauwe, John K, Crane, Paul K, Haines, Jonathan L, Mayeux, Richard, Pericak-Vance, Margaret A, Farrer, Lindsay A, Schellenberg, Gerard D, Parisi, Joseph E, Petersen, Ronald C, Graff-Radford, Neill R, Dickson, Dennis W, Younkin, Steven G, Ertekin-Taner, Nilüfer
格式: Artigo
語言:Inglês
出版: BioMed Central 2014
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4198935/
https://ncbi.nlm.nih.gov/pubmed/25324900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt268
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