Brain Expression Genome-Wide Association Study (eGWAS) Identifies Human Disease-Associated Variants

Genetic variants that modify brain gene expression may also influence risk for human diseases. We measured expression levels of 24,526 transcripts in brain samples from the cerebellum and temporal cortex of autopsied subjects with Alzheimer's disease (AD, cerebellar n = 197, temporal cortex n =...

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Detalhes bibliográficos
Main Authors: Zou, Fanggeng, Chai, High Seng, Younkin, Curtis S., Allen, Mariet, Crook, Julia, Pankratz, V. Shane, Carrasquillo, Minerva M., Rowley, Christopher N., Nair, Asha A., Middha, Sumit, Maharjan, Sooraj, Nguyen, Thuy, Ma, Li, Malphrus, Kimberly G., Palusak, Ryan, Lincoln, Sarah, Bisceglio, Gina, Georgescu, Constantin, Kouri, Naomi, Kolbert, Christopher P., Jen, Jin, Haines, Jonathan L., Mayeux, Richard, Pericak-Vance, Margaret A., Farrer, Lindsay A., Schellenberg, Gerard D., Petersen, Ronald C., Graff-Radford, Neill R., Dickson, Dennis W., Younkin, Steven G., Ertekin-Taner, Nilüfer
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369937/
https://ncbi.nlm.nih.gov/pubmed/22685416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002707
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