Brain Expression Genome-Wide Association Study (eGWAS) Identifies Human Disease-Associated Variants

Genetic variants that modify brain gene expression may also influence risk for human diseases. We measured expression levels of 24,526 transcripts in brain samples from the cerebellum and temporal cortex of autopsied subjects with Alzheimer's disease (AD, cerebellar n = 197, temporal cortex n =...

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主要な著者: Zou, Fanggeng, Chai, High Seng, Younkin, Curtis S., Allen, Mariet, Crook, Julia, Pankratz, V. Shane, Carrasquillo, Minerva M., Rowley, Christopher N., Nair, Asha A., Middha, Sumit, Maharjan, Sooraj, Nguyen, Thuy, Ma, Li, Malphrus, Kimberly G., Palusak, Ryan, Lincoln, Sarah, Bisceglio, Gina, Georgescu, Constantin, Kouri, Naomi, Kolbert, Christopher P., Jen, Jin, Haines, Jonathan L., Mayeux, Richard, Pericak-Vance, Margaret A., Farrer, Lindsay A., Schellenberg, Gerard D., Petersen, Ronald C., Graff-Radford, Neill R., Dickson, Dennis W., Younkin, Steven G., Ertekin-Taner, Nilüfer
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
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Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369937/
https://ncbi.nlm.nih.gov/pubmed/22685416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002707
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