Evaluation of Memory Endophenotypes for Association with CLU, CR1 and PICALM variants in African-American and Caucasian Subjects

BACKGROUND: Genetic variants at the CLU, CR1 and PICALM loci associate with risk for late-onset Alzheimer’s disease (LOAD) in genome-wide association studies (GWAS). In this study, our aim was to determine whether the LOAD risk variants at these three loci influence memory endophenotypes in African-...

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Main Authors: Pedraza, Otto, Allen, Mariet, Jennette, Kyle, Carrasquillo, Minerva, Crook, Julia, Serie, Daniel, Pankratz, V. Shane, Palusak, Ryan, Nguyen, Thuy, Malphrus, Kimberly, Ma, Li, Bisceglio, Gina, Roberts, Rosebud O., Lucas, John A., Ivnik, Robert J., Smith, Glenn E., Graff-Radford, Neill R., Petersen, Ronald C., Younkin, Steven G., Ertekin-Taner, Nilüfer
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815516/
https://ncbi.nlm.nih.gov/pubmed/23643458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2013.01.016
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