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Association Studies between Common Variants in Prolyl isomerase Pin1 and the Risk for Late-Onset Alzheimer's Disease
Alzheimer's disease (AD) pathology is associated with two proteins, the microtubule-binding protein tau and the amyloid-precursor protein (APP). When tau becomes hyperphosphorylated, it forms neuritic aggregates, called neurofibrillary tangles. APP is cleaved by several enzymes to generate Aβ p...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1952685/ https://ncbi.nlm.nih.gov/pubmed/17482359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2007.03.071 |
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