Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-β signaling

Transforming growth factor (TGF)-β plays a pivotal role in regulation of progression of cancer through effects on tumor microenvironment as well as on cancer cells. TGF-β inhibitors have recently been shown to prevent the growth and metastasis of certain cancers. However, there may be adverse effect...

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Main Authors: Kano, Mitsunobu R., Bae, Younsoo, Iwata, Caname, Morishita, Yasuyuki, Yashiro, Masakazu, Oka, Masako, Fujii, Tomoko, Komuro, Akiyoshi, Kiyono, Kunihiko, Kaminishi, Michio, Hirakawa, Kosei, Ouchi, Yasuyoshi, Nishiyama, Nobuhiro, Kataoka, Kazunori, Miyazono, Kohei
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800736/
https://ncbi.nlm.nih.gov/pubmed/17307870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611660104
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