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Enhanced Percolation and Gene Expression in Tumor Hypoxia by PEGylated Polyplex Micelles
In regard to gene vectors for cancer gene therapy, their percolation into the tumor tissue should be essential for successful outcome. Here, we studied the tumor penetrability of nonviral vectors (polyplexes) after incubation with the multicellular tumor spheroid (MCTS) models and intratumoral (i.t....
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2835242/ https://ncbi.nlm.nih.gov/pubmed/19471245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.119 |
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