Enhanced Percolation and Gene Expression in Tumor Hypoxia by PEGylated Polyplex Micelles

In regard to gene vectors for cancer gene therapy, their percolation into the tumor tissue should be essential for successful outcome. Here, we studied the tumor penetrability of nonviral vectors (polyplexes) after incubation with the multicellular tumor spheroid (MCTS) models and intratumoral (i.t....

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Han, Muri, Oba, Makoto, Nishiyama, Nobuhiro, Kano, Mitsunobu R, Kizaka-Kondoh, Shinae, Kataoka, Kazunori
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2009
विषय:
Original Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835242/
https://ncbi.nlm.nih.gov/pubmed/19471245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.119
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