Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-β signaling

Transforming growth factor (TGF)-β plays a pivotal role in regulation of progression of cancer through effects on tumor microenvironment as well as on cancer cells. TGF-β inhibitors have recently been shown to prevent the growth and metastasis of certain cancers. However, there may be adverse effect...

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Główni autorzy: Kano, Mitsunobu R., Bae, Younsoo, Iwata, Caname, Morishita, Yasuyuki, Yashiro, Masakazu, Oka, Masako, Fujii, Tomoko, Komuro, Akiyoshi, Kiyono, Kunihiko, Kaminishi, Michio, Hirakawa, Kosei, Ouchi, Yasuyoshi, Nishiyama, Nobuhiro, Kataoka, Kazunori, Miyazono, Kohei
Format: Artigo
Język:Inglês
Wydane: National Academy of Sciences 2007
Hasła przedmiotowe:
Biological Sciences
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800736/
https://ncbi.nlm.nih.gov/pubmed/17307870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611660104
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