Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-β signaling

Transforming growth factor (TGF)-β plays a pivotal role in regulation of progression of cancer through effects on tumor microenvironment as well as on cancer cells. TGF-β inhibitors have recently been shown to prevent the growth and metastasis of certain cancers. However, there may be adverse effect...

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Detalhes bibliográficos
Main Authors: Kano, Mitsunobu R., Bae, Younsoo, Iwata, Caname, Morishita, Yasuyuki, Yashiro, Masakazu, Oka, Masako, Fujii, Tomoko, Komuro, Akiyoshi, Kiyono, Kunihiko, Kaminishi, Michio, Hirakawa, Kosei, Ouchi, Yasuyoshi, Nishiyama, Nobuhiro, Kataoka, Kazunori, Miyazono, Kohei
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800736/
https://ncbi.nlm.nih.gov/pubmed/17307870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611660104
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