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Suppression of β-Amyloid Precursor Protein Signaling into the Nucleus by Estrogens Mediated through Complex Formation between the Estrogen Receptor and Fe65
The C-terminal fragment of the β-amyloid precursor protein produced after cleavage by γ-secretase, namely, APPct or AICD, has been shown to form a multimeric complex with the adaptor protein Fe65 and to regulate transcription through the recruitment of the histone acetyltransferase Tip60. The presen...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1800721/ https://ncbi.nlm.nih.gov/pubmed/17130235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01280-06 |
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