Suppression of β-Amyloid Precursor Protein Signaling into the Nucleus by Estrogens Mediated through Complex Formation between the Estrogen Receptor and Fe65

The C-terminal fragment of the β-amyloid precursor protein produced after cleavage by γ-secretase, namely, APPct or AICD, has been shown to form a multimeric complex with the adaptor protein Fe65 and to regulate transcription through the recruitment of the histone acetyltransferase Tip60. The presen...

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Hlavní autoři: Bao, Junying, Cao, Chuanhai, Zhang, Xiaohui, Jiang, Feng, Nicosia, Santo V., Bai, Wenlong
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1800721/
https://ncbi.nlm.nih.gov/pubmed/17130235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01280-06
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