Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM

The human neurodegenerative and cancer predisposition condition ataxia-telangiectasia is characterized at the cellular level by radiosensitivity, chromosomal instability, and impaired induction of ionizing radiation-induced cell cycle checkpoint controls. Recent work has revealed that the gene defec...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Smith, Graeme C. M., Cary, Robert B., Lakin, Nicholas D., Hann, Byron C., Teo, Soo-Hwang, Chen, David J., Jackson, Stephen P.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17999/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10500142/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.20.11134
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