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Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM

The human neurodegenerative and cancer predisposition condition ataxia-telangiectasia is characterized at the cellular level by radiosensitivity, chromosomal instability, and impaired induction of ionizing radiation-induced cell cycle checkpoint controls. Recent work has revealed that the gene defec...

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Detalhes bibliográficos
Main Authors: Smith, Graeme C. M., Cary, Robert B., Lakin, Nicholas D., Hann, Byron C., Teo, Soo-Hwang, Chen, David J., Jackson, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17999/
https://ncbi.nlm.nih.gov/pubmed/10500142
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