Kinetic properties of mutant deoxyguanosine kinase in a case of reversible hepatic mtDNA depletion

DGUOK [dG (deoxyguanosine) kinase] is one of the two mitochondrial deoxynucleoside salvage pathway enzymes involved in precursor synthesis for mtDNA (mitochondrial DNA) replication. DGUOK is responsible for the initial rate-limiting phosphorylation of the purine deoxynucleosides, using a nucleoside...

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Hlavní autoři: Mousson de camaret, Bénédicte, Taanman, Jan-Willem, Padet, Sylvie, Chassagne, Maïté, Mayençon, Martine, Clerc-Renaud, Pascale, Mandon, Ginette, Zabot, Marie-Thérèse, Lachaux, Alain, Bozon, Dominique
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2007
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798436/
https://ncbi.nlm.nih.gov/pubmed/17073823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060705
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