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Cr(VI)-stimulated STAT3 tyrosine phosphorylation and nuclear translocation in human airway epithelial cells requires Lck

Chronic inhalation of low amounts of Cr(VI) promotes pulmonary diseases and cancers through poorly defined mechanisms. SFKs (Src family kinases) in pulmonary airway cells may mediate Cr(VI) signalling for lung injury, although the downstream effectors of Cr(VI)-stimulated SFKs and how they relate to...

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Main Authors: O'hara, Kimberley A., Vaghjiani, Rasilaben J., Nemec, Antonia A., Klei, Linda R., Barchowsky, Aaron
格式: Artigo
語言:Inglês
出版: Portland Press Ltd. 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798428/
https://ncbi.nlm.nih.gov/pubmed/17078813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061427
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