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Chromium (VI) Inhibits Heme Oxygenase-1 Expression In Vivo and in Arsenic-Exposed Human Airway Epithelial Cells

Inhaled hexavalent chromium (Cr(VI)) promotes lung injury and pulmonary diseases through poorly defined mechanisms. One hypothesis for this lung pathogenesis is that Cr(VI) silences induction of cytoprotective genes, such as heme oxygenase-1 (HO-1), whose total lung mRNA levels were reduced 21 days...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: O’HARA, KIMBERLEY A., NEMEC, ANTONIA A., ALAM, JAWED, KLEI, LINDA R., MOSSMAN, BROOKE T., BARCHOWSKY, AARON
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288750/
https://ncbi.nlm.nih.gov/pubmed/16775837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.20710
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