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Cr(VI)-stimulated STAT3 tyrosine phosphorylation and nuclear translocation in human airway epithelial cells requires Lck

Chronic inhalation of low amounts of Cr(VI) promotes pulmonary diseases and cancers through poorly defined mechanisms. SFKs (Src family kinases) in pulmonary airway cells may mediate Cr(VI) signalling for lung injury, although the downstream effectors of Cr(VI)-stimulated SFKs and how they relate to...

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Autori principali: O'hara, Kimberley A., Vaghjiani, Rasilaben J., Nemec, Antonia A., Klei, Linda R., Barchowsky, Aaron
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798428/
https://ncbi.nlm.nih.gov/pubmed/17078813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061427
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