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Cr(VI)-stimulated STAT3 tyrosine phosphorylation and nuclear translocation in human airway epithelial cells requires Lck

Chronic inhalation of low amounts of Cr(VI) promotes pulmonary diseases and cancers through poorly defined mechanisms. SFKs (Src family kinases) in pulmonary airway cells may mediate Cr(VI) signalling for lung injury, although the downstream effectors of Cr(VI)-stimulated SFKs and how they relate to...

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Detalhes bibliográficos
Main Authors: O'hara, Kimberley A., Vaghjiani, Rasilaben J., Nemec, Antonia A., Klei, Linda R., Barchowsky, Aaron
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1798428/
https://ncbi.nlm.nih.gov/pubmed/17078813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061427
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