Simple Colorimetric Inhibition Assay of Heme Crystallization for High-Throughput Screening of Antimalarial Compounds

Current assays for screening new antimalarials need initiators of β-hematin formation that require laborious preparation, special devices, and substrates. In this study, based on reduction of heme absorption in β-hematin formation, we developed a simple colorimetric assay using Tween 20 as an initia...

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Bibliographic Details
Main Authors: Huy, Nguyen Tien, Uyen, Dinh Thanh, Maeda, Atsushi, Trang, Dai Thi Xuan, Oida, Tatsuo, Harada, Shigeharu, Kamei, Kaeko
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Analytical Procedures
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797674/
https://ncbi.nlm.nih.gov/pubmed/17088494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00985-06
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