Effect of Inducers, Incubation Time and Heme Concentration on IC(50) Value Variation in Anti-heme Crystallization Assay

Heme detoxification through crystallization into hemozoin has been suggested as a good target for the development of screening assays for new antimalarials. However, comparisons among the data obtained from different experiments are difficult, and the IC(50) values (the concentrations of drug that a...

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Detalhes bibliográficos
Main Authors: Nhien, Nguyen Thanh Thuy, Huy, Nguyen Tien, Uyen, Dinh Thanh, Deharo, Eric, Hoa, Pham Thi Le, Hirayama, Kenji, Harada, Shigeharu, Kamei, Kaeko
Formato: Artigo
Idioma:Inglês
Publicado em: The Japanese Society of Tropical Medicine 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289280/
https://ncbi.nlm.nih.gov/pubmed/22438701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2149/tmh.2011-29
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