Effect of Inducers, Incubation Time and Heme Concentration on IC(50) Value Variation in Anti-heme Crystallization Assay

Heme detoxification through crystallization into hemozoin has been suggested as a good target for the development of screening assays for new antimalarials. However, comparisons among the data obtained from different experiments are difficult, and the IC(50) values (the concentrations of drug that a...

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Main Authors: Nhien, Nguyen Thanh Thuy, Huy, Nguyen Tien, Uyen, Dinh Thanh, Deharo, Eric, Hoa, Pham Thi Le, Hirayama, Kenji, Harada, Shigeharu, Kamei, Kaeko
Format: Artigo
Jezik:Inglês
Izdano: The Japanese Society of Tropical Medicine 2011
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289280/
https://ncbi.nlm.nih.gov/pubmed/22438701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2149/tmh.2011-29
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