Colorimetric High-Throughput Screen for Detection of Heme Crystallization Inhibitors

Malaria infects 500 million people annually, a number that is likely to rise as drug resistance to currently used antimalarials increases. During its intraerythrocytic stage, the causative parasite, Plasmodium falciparum, metabolizes hemoglobin and releases toxic heme, which is neutralized by a para...

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Главные авторы: Rush, Margaret A., Baniecki, Mary Lynn, Mazitschek, Ralph, Cortese, Joseph F., Wiegand, Roger, Clardy, Jon, Wirth, Dyann F.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2009
Предметы:
Analytical Procedures
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687197/
https://ncbi.nlm.nih.gov/pubmed/19307367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01466-08
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