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Bilayer deformation by the Kv channel voltage sensor domain revealed by self-assembly simulations
Coarse-grained molecular dynamics simulations are used to explore the interaction with a phospholipid bilayer of the voltage sensor (VS) domain and the S4 helix from the archaebacterial voltage-gated potassium (Kv) channel KvAP. Multiple 2-μs self-assembly simulations reveal that the isolated S4 hel...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1797625/ https://ncbi.nlm.nih.gov/pubmed/17301243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606822104 |
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