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Interaction of Diverse Voltage Sensor Homologs with Lipid Bilayers Revealed by Self-Assembly Simulations

Voltage sensors (VS) domains couple the activation of ion channels/enzymes to changes in membrane voltage. We used molecular dynamics simulations to examine interactions with lipids of several VS homologs. VSs in intact channels in the activated state are exposed to phospholipids, leading to a chara...

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Bibliografiske detaljer
Main Authors: Mokrab, Younes, Sansom, Mark S.P.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037555/
https://ncbi.nlm.nih.gov/pubmed/21320431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.11.049
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