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Prion Interference Is Due to a Reduction in Strain-Specific PrP(Sc) Levels

When two prion strains infect a single host, one strain can interfere with the ability of the other to cause disease but it is not known whether prion replication of the second strain is also diminished. To further investigate strain interference, we infected hamsters in the sciatic nerve with the l...

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Main Authors: Bartz, Jason C., Kramer, Michelle L., Sheehan, Meghan H., Hutter, Jessica A. L., Ayers, Jacob I., Bessen, Richard A., Kincaid, Anthony E.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797475/
https://ncbi.nlm.nih.gov/pubmed/17079313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01751-06
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