Repression of Interferon Regulatory Factor 1 by Hepatitis C Virus Core Protein Results in Inhibition of Antiviral and Immunomodulatory Genes

Hepatitis C virus (HCV) proteins are known to interfere at several levels with both innate and adaptive responses of the host. A key target in these effects is the interferon (IFN) signaling pathway. While the effects of nonstructural proteins are well established, the role of structural proteins re...

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Bibliographic Details
Main Authors: Ciccaglione, Anna R., Stellacci, Emilia, Marcantonio, Cinzia, Muto, Valentina, Equestre, Michele, Marsili, Giulia, Rapicetta, Maria, Battistini, Angela
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Cellular Response to Infection
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797261/
https://ncbi.nlm.nih.gov/pubmed/17050603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01011-06
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