p66 Shc and tyrosine-phosphorylated Shc in primary breast tumors identify patients likely to relapse despite tamoxifen therapy

INTRODUCTION: Shc adapter proteins are secondary messenger proteins involved in various cellular pathways, including those mediating receptor tyrosine kinase signaling and apoptosis in response to stress. We have previously reported that high levels of tyrosine-phosphorylated Shc (PY-Shc) and low le...

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Main Authors: Frackelton, A Raymond, Lu, Li, Davol, Pamela A, Bagdasaryan, Robert, Hafer, Laurie J, Sgroi, Dennis C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797038/
https://ncbi.nlm.nih.gov/pubmed/17196107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1631
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