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Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux

Aceruloplasminemia is an autosomal recessive disorder of iron metabolism. Affected individuals evidence iron accumulation in tissue parenchyma in association with absent serum ceruloplasmin. Genetic studies of such patients reveal inherited mutations in the ceruloplasmin gene. To elucidate the role...

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Detalhes bibliográficos
Main Authors: Harris, Z. Leah, Durley, Alison P., Man, Tsz Kwong, Gitlin, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17965/
https://ncbi.nlm.nih.gov/pubmed/10485908
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