Ceruloplasmin and hephaestin jointly protect the exocrine pancreas against oxidative damage by facilitating iron efflux

Little is known about the iron efflux from the pancreas, but it is likely that multicopper ferroxidases (MCFs) are involved in this process. We thus used hephaestin (Heph) and ceruloplasmin (Cp) single-knockout mice and Heph/Cp double-knockout mice to investigate the roles of MCFs in pancreatic iron...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Chen, Min, Zheng, Jiashuo, Liu, Guohao, Xu, En, Wang, Junzhuo, Fuqua, Brie K., Vulpe, Chris D., Anderson, Gregory J., Chen, Huijun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007082/
https://ncbi.nlm.nih.gov/pubmed/29883959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.05.013
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