CpG DNA activation and plasma-cell differentiation of CD27(−) naive human B cells

Unmethylated CpG DNA activation of naive CD27(−) B cells has been reported to require B-cell–receptor (BCR) cross-linking. We describe a culture system using CpG DNA with sequential steps for T-cell–independent activation of naive CD19(+)CD27(−) human peripheral blood B cells that induces efficient...

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Bibliografski detalji
Glavni autori: Huggins, Jennifer, Pellegrin, Tina, Felgar, Raymond E., Wei, Chungwen, Brown, Miguel, Zheng, Bo, Milner, Eric C. B., Bernstein, Steven H., Sanz, Ignacio, Zand, Martin S.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2007
Teme:
Immunobiology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794051/
https://ncbi.nlm.nih.gov/pubmed/17032927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-03-008441
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