Apoptosis and complement-mediated lysis of myeloma cells by polyclonal rabbit antithymocyte globulin

Current monoclonal antibody therapies for multiple myeloma have had limited success, perhaps due to narrow target specificity. We have previously described the ability of polyclonal rabbit antithymocyte globulin (rATG) to induce caspase- and cathepsin-mediated apoptosis in human B and plasma cells....

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Detalhes bibliográficos
Main Authors: Zand, Martin S., Vo, Thuong, Pellegrin, Tina, Felgar, Raymond, Liesveld, Jane L., Ifthikharuddin, Jainulabdeen J., Abboud, Camille N., Sanz, Ignacio, Huggins, Jennifer
Formato: Artigo
Idioma:Inglês
Publicado em: © 2006 by The American Society of Hematology 2006
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895388/
https://ncbi.nlm.nih.gov/pubmed/16368890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2269
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