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Structural basis for transcription inhibition by tagetitoxin
Tagetitoxin (Tgt) inhibits plastid-encoded, bacterial and some eukaryotic RNA polymerases (RNAPs) by an unknown mechanism. A 2.4Å-resolution structure of the Thermus thermophilus RNAP/Tgt complex revealed that Tgt-binding site within the RNAP secondary channel overlaps with that of the stringent con...
में बचाया:
| मुख्य लेखकों: | , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2005
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1790907/ https://ncbi.nlm.nih.gov/pubmed/16273103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1015 |
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