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Structural Basis for Converting a General Transcription Factor into an Operon-Specific Virulence Regulator

RfaH, a paralog of the general transcription factor NusG, is recruited to elongating RNA polymerase at specific regulatory sites. The X-ray structure of Escherichia coli RfaH reported here reveals two domains. The N-terminal domain displays high similarity to that of NusG. In contrast, the α-helical...

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Autori principali: Belogurov, Georgiy A., Vassylyeva, Marina N., Svetlov, Vladimir, Klyuyev, Sergiy, Grishin, Nick V., Vassylyev, Dmitry G., Artsimovitch, Irina
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116145/
https://ncbi.nlm.nih.gov/pubmed/17434131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.02.021
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