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Structural Basis for Converting a General Transcription Factor into an Operon-Specific Virulence Regulator
RfaH, a paralog of the general transcription factor NusG, is recruited to elongating RNA polymerase at specific regulatory sites. The X-ray structure of Escherichia coli RfaH reported here reveals two domains. The N-terminal domain displays high similarity to that of NusG. In contrast, the α-helical...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3116145/ https://ncbi.nlm.nih.gov/pubmed/17434131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.02.021 |
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