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Evidence that Membrane Insertion of the Cytosolic Domain of Bcl-x(L) is Governed by an Electrostatic Mechanism

Signals from different cellular networks are integrated at the mitochondria in the regulation of apoptosis. This integration is controlled by the Bcl-2 proteins, many of which change localization fromthe cytosol to the mitochondrial outer membrane in this regulation. For Bcl-x(L), this change in loc...

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Detalhes bibliográficos
Main Authors: Thuduppathy, Guruvasuthevan R., Craig, Jeffrey W., Schon, Victoria Kholodenko Arne, Hill, R. Blake
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785297/
https://ncbi.nlm.nih.gov/pubmed/16650855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.03.052
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