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Acid destabilization of the solution conformation of Bcl-X(L) does not drive its pH-dependent insertion into membranes

Regulation of programmed cell death by Bcl-x(L) is dependent on both its solution and integral membrane conformations. A conformational change from solution to membrane is also important in this regulation. This conformational change shows a pH-dependence similar to the translocation domain of dipht...

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Hlavní autoři: Thuduppathy, Guruvasuthevan R., Hill, R. Blake
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1752203/
https://ncbi.nlm.nih.gov/pubmed/16385002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051807706
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