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Acid destabilization of the solution conformation of Bcl-X(L) does not drive its pH-dependent insertion into membranes
Regulation of programmed cell death by Bcl-x(L) is dependent on both its solution and integral membrane conformations. A conformational change from solution to membrane is also important in this regulation. This conformational change shows a pH-dependence similar to the translocation domain of dipht...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1752203/ https://ncbi.nlm.nih.gov/pubmed/16385002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051807706 |
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