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The N-Terminal Domain of Bcl-xL Reversibly Binds Membranes in a pH-Dependent Manner

Bcl-x(L) regulates apoptosis by maintaining the integrity of the mitochondrial outer membrane by adopting both soluble and membrane-associated forms. The membrane-associated conformation does not require a conserved, C-terminal transmembrane domain and appears to be inserted into the bilayer of synt...

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Detalhes bibliográficos
Main Authors: Thuduppathy, Guruvasuthevan R., Terrones, Oihana, Craig, Jeffrey W., Basañez, Gorka, Hill, R. Blake
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1764622/
https://ncbi.nlm.nih.gov/pubmed/17128992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0616652
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