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The N-Terminal Domain of Bcl-xL Reversibly Binds Membranes in a pH-Dependent Manner
Bcl-x(L) regulates apoptosis by maintaining the integrity of the mitochondrial outer membrane by adopting both soluble and membrane-associated forms. The membrane-associated conformation does not require a conserved, C-terminal transmembrane domain and appears to be inserted into the bilayer of synt...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1764622/ https://ncbi.nlm.nih.gov/pubmed/17128992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0616652 |
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