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Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus

Nanoparticles larger than the reported mesh-pore size range (10–200 nm) in mucus have been thought to be much too large to undergo rapid diffusional transport through mucus barriers. However, large nanoparticles are preferred for higher drug encapsulation efficiency and the ability to provide sustai...

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Autors principals: Lai, Samuel K., O'Hanlon, D. Elizabeth, Harrold, Suzanne, Man, Stan T., Wang, Ying-Ying, Cone, Richard, Hanes, Justin
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785284/
https://ncbi.nlm.nih.gov/pubmed/17244708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608611104
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