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The Cooperative Response of Synaptotagmin I C2A. A Hypothesis for a Ca(2+)-Driven Molecular Hammer
In the current understanding of exocytosis at the nerve terminal, the C2 domain of synaptotagmin (C2A) is presumed to bind Ca(2+) and the membrane in a stepwise fashion: cation then membrane as cation increases the affinity of protein for membrane. Fluorescence spectroscopy data were gathered over a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1783886/ https://ncbi.nlm.nih.gov/pubmed/17114221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.087197 |
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