DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8(+) T cells in a spectrum of human MHC I haplotypes

Optimal HIV vaccines should elicit CD8(+) T cells specific for HIV proteins presented on MHC class I products, because these T cells contribute to host resistance to viruses. We had previously found that the targeting of antigen to dendritic cells (DCs) in mice efficiently induces CD8(+) T cell resp...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Bozzacco, Leonia, Trumpfheller, Christine, Siegal, Frederick P., Mehandru, Saurabh, Markowitz, Martin, Carrington, Mary, Nussenzweig, Michel C., Piperno, Angela Granelli, Steinman, Ralph M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783096/
https://ncbi.nlm.nih.gov/pubmed/17229838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610383104
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky