Epitope-specific crosslinking of CD45 down-regulates membrane-associated tyrosine phosphatase activity and triggers early signalling events in human activated T cells

CD45 engagement by monoclonal antibodies on human activated T cells triggers tumour necrosis factor-α (TNF-α) gene transcription in an epitope-specific manner. To dissect the early signalling events leading to TNF-α gene expression, we established that CD45 crosslinking resulted in tyrosine phosphor...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Spertini, François, Perret-Menoud, Veronique, Barbier, Nathalie, Chatila, Talal, Barbey, Catherine, Corthesy, Blaise
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Science Inc 2004
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782601/
https://ncbi.nlm.nih.gov/pubmed/15554922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.01986.x
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak