Astragaloside II triggers T cell activation through regulation of CD45 protein tyrosine phosphatase activity

AIM: To investigate the immunomodulating activity of astragalosides, the active compounds from a traditional tonic herb Astragalus membranaceus Bge, and to explore the molecular mechanisms underlying the actions, focusing on CD45 protein tyrosine phosphatase (CD45 PTPase), which plays a critical rol...

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Detalhes bibliográficos
Main Authors: Wan, Chun-ping, Gao, Li-xin, Hou, Li-fei, Yang, Xiao-qian, He, Pei-lan, Yang, Yi-fu, Tang, Wei, Yue, Jian-min, Li, Jia, Zuo, Jian-ping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002795/
https://ncbi.nlm.nih.gov/pubmed/23524573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.208
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