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Contribution of αβ and γδ T cells to the generation of primary immunoglobulin G-driven autoimmune response in immunoglobulin-µ-deficient/lpr mice

Class switch recombination (CSR) is a T-cell-dependent mechanism regulating isotype switching in activated mature B cells. Recently we showed that T-cell-independent CSRs occur spontaneously during B lymphopoiesis, but such cells are negatively selected by Fas signalling. In immunoglobulin µ-deficie...

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Hlavní autoři: Seagal, Jane, Melamed, Doron
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782487/
https://ncbi.nlm.nih.gov/pubmed/15147570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.01883.x
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